Query: NC_009092:179226 Shewanella loihica PV-4, complete genome Lineage: Shewanella loihica; Shewanella; Shewanellaceae; Alteromonadales; Proteobacteria; Bacteria General Information: This strain is an environmental isolate from the Naha Vents, Hawaii, in the Pacific Ocean. Psychrotolerant bacterium. This genus includes species that inhabit a wide range of environments and are capable of utilizing a wide variety of electron acceptors during anaerobic respiration including some insoluble metal oxides while using very few carbon sources such as lactate or acetate. This group of organisms have been studied extensively for their electron transport systems. Shewanella loihica is a psychrotolerant deep sea bacterium. This organism is able to reduce iron, manganese and uranium and may be useful for bioremediation at low temperatures.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.