Query: NC_009012:3421000 Clostridium thermocellum ATCC 27405, complete genome Lineage: Clostridium thermocellum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria General Information: This strain is a well studied producer of endoglucanase and several restriction endonucleases. Thermophilic cellulose degrading bacterium. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a thermophilic anaerobe that produces an extracellular enzyme system capable of degrading crystalline cellulose to soluble sugars that are further utilized as the carbon source for growth.
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General Information: Originally identified as Pseudomonas sp. LB400 that was found in contaminated soil in upstate New York, USA, this organism is now classified in the genus Burkholderia. Polychlorinated biphenyl-degrading bacterium. Member of the genus Burkholderia are versatile organisms that occupy a surprisingly wide range of ecological niches. These bacteria are exploited for biocontrol, bioremediation, and plant growth promotion purposes. Burkholderia xenovorans has been found on fungi, animals, and from human clinical isolates such as from cystic fibrosis (CF) patients. It may be tightly associated with white-rot fungus, as the degadation of lignin by the fungus results in aromatic compounds the bacterium can then degrade. This organism is exceptionally capable of degradation of polychlorinated biphenyls (PCBs), which are environmental pollutants, and thus it may play a role in bioremediation of polluted and toxic sites and is studied as a model bioremediator. PCBs can be utilized as the sole carbon and energy source by this organism. The pathways for degradation of PCBs have been extensively characterized at both the genetic and the molecular level and have become a model system for the bacterial breakdown of these very persistent environmental contaminants.