Query: NC_008836:1072721 Burkholderia mallei NCTC 10229 chromosome II, complete sequence Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.
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General Information: Environment: Soil, Terrestrial; Temp: Mesophile. Streptomyces violaceusniger 16S rRNA gene clade form a gray aerial spore mass and a grayish-yellow substrate mycelium on oatmeal agar, and produce aerial hyphae that differentiate into spiral chains of rugose ornamented spores. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin.