Pre_GI: SWBIT SVG BLASTN

Query: NC_008800:2127918 Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,

Lineage: Yersinia enterocolitica; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This isolate (strain 8081; NCTC 13174) is a mouse-lethal serotype of Yersinia enterocolitica that contains a high pathogenicity island (HPI) that encodes an iron uptake system (yersiniabactin) and a type II secretion system. Causes gastroenteritis. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. This species is a food and waterborn pathogen that causes gastroenteritis (inflammation of the mucous membranes of the stomach and intestine) and is able to proliferate at temperatures as low as 4 degrees C.

Subject: NC_003485:1707653 Streptococcus pyogenes MGAS8232, complete genome

Lineage: Streptococcus pyogenes; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This strain is a serotype M18 strain often associated with acute rheumatic fever outbreaks in the USA. Causes tonsilitis. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is a member of the normal human nasopharyngeal flora. S. pyogenes is a group A streptococcus and is the leading cause of uncomplicated bacterial pharyngitis and tonsillitis. This organism is commonly referred to by the lay press as "flesh eating bacteria".