Query: NC_008783:671349 Bartonella bacilliformis KC583, complete genome Lineage: Bartonella bacilliformis; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Cauative agent of Carrion's disease. Like other members of this genus, Bartonella bacilliformis is an obligate intracellular parasite, which infects red blood cells. Bartonella bacilliformis is the causative agent of Carrion's disease, also called Oroya fever. This disease is found in the western Andes of South America, and is transmitted through an insect vector. Carrion's disease is characterized by an acute, febrile, anemia with a mortality of 40 to 90%. The anemic phase may be followed by a milder secondary episode, characterized by wart-like skin lesions.
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General Information: A nematode endosymbiont. This group of bacteria are associated with a variety of invertebrate species, some as pathogens, some in a symbiotic relationship. Typically these organisms are transmitted maternally from mother to daughter transovarially (through the egg) although these bacteria can affect their hosts reproductive capabilities in order to enhance transmission. The net outcome is the increase of hosts carrying the bacteria in the next generation, thereby increasing transmission. This strain naturally infects Brugia malayi, a parasitic filarial nematode that causes lymphatic filariasis, one of the most devastating diseases in humans. The endosymbiont plays important roles in the biology of the nematide host. One of the known such effects are aberrant sex ratios in the host, parthenogenesis and feminization of genetic males, etc.