Query: NC_008783:1101973 Bartonella bacilliformis KC583, complete genome
Lineage: Bartonella bacilliformis; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Cauative agent of Carrion's disease. Like other members of this genus, Bartonella bacilliformis is an obligate intracellular parasite, which infects red blood cells. Bartonella bacilliformis is the causative agent of Carrion's disease, also called Oroya fever. This disease is found in the western Andes of South America, and is transmitted through an insect vector. Carrion's disease is characterized by an acute, febrile, anemia with a mortality of 40 to 90%. The anemic phase may be followed by a milder secondary episode, characterized by wart-like skin lesions.
Subject: NC_012808:1220378 Methylobacterium extorquens AM1, complete genome
Lineage: Methylobacterium extorquens; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.