Query: NC_008699:2916752 Nocardioides sp. JS614, complete genome
Lineage: Nocardioides; Nocardioides; Nocardioidaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This bacterium grows quickly and efficiently on media containing vinyl chloride and ethene. If starved of vinyl chloride for one day, it will not recover for more than 40 days. This strain was placed in the Nocardioides genus on the basis of 16S rRNA analysis.
Subject: NC_008611:1015138 Mycobacterium ulcerans Agy99, complete genome
Lineage: Mycobacterium ulcerans; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This organism causes Buruli ulcer and is the third most common mycobacterial pathogen after Mycobacterium tuberculosis and Mycobacterium leprae. The disease has increased dramatically through central and West Africa since the late 1980s. Causative agent of Buruli and Bairnsdale ulcer. Infection by Mycobacterium ulcerans causes the formation of skin ulcers which, if left untreated, can lead to extensive scarring and/or amputation. Mycobacterium ulcerans produces a cytotoxin, mycolactone, which causes the destruction of skin tissue seen in this disease. This organism is resistant to antibiotics and treatment involves the surgical removal of infected tissues.