Pre_GI: SWBIT SVG BLASTN

Query: NC_008611:1015138 Mycobacterium ulcerans Agy99, complete genome

Lineage: Mycobacterium ulcerans; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This organism causes Buruli ulcer and is the third most common mycobacterial pathogen after Mycobacterium tuberculosis and Mycobacterium leprae. The disease has increased dramatically through central and West Africa since the late 1980s. Causative agent of Buruli and Bairnsdale ulcer. Infection by Mycobacterium ulcerans causes the formation of skin ulcers which, if left untreated, can lead to extensive scarring and/or amputation. Mycobacterium ulcerans produces a cytotoxin, mycolactone, which causes the destruction of skin tissue seen in this disease. This organism is resistant to antibiotics and treatment involves the surgical removal of infected tissues.

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BLASTN Alignment.txt

Subject: NC_018583:95388 Gordonia sp. KTR9 plasmid pGKT3, complete sequence

Lineage: Gordonia; Gordonia; Gordoniaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from soil at an explosives testing facility. Can transform hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), a cyclic nitramine explosive. Many military ranges in the United States and Canada are contaminated with explosive and propellant residues. Of the nitroaromatic and nitramine explosives that exist on these sites, hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) has a low sorption capacity and can migrate through soil into surface water and groundwater.