Query: NC_008596:421882 Mycobacterium smegmatis str. MC2 155, complete genome
Lineage: Mycobacterium smegmatis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Causes opportunistic infections. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium smegmatis was initially isolated from human smegma. It is associated with soft tissue lesions following trauma or surgery. It is also reported as a possible factor in penile carcinogenesis.
Subject: NC_015711:6522808 Myxococcus fulvus HW-1 chromosome, complete genome
Lineage: Myxococcus fulvus; Myxococcus; Myxococcaceae; Myxococcales; Proteobacteria; Bacteria
General Information: This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Myxococcus fulvus produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.