Pre_GI: SWBIT SVG BLASTN

Query: NC_008369:514995 Francisella tularensis subsp. holarctica OSU18, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: Isolated from a beaver that died of tularemia in Oklahoma in 1978. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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BLASTN Alignment.txt

Subject: NC_002677:2571310 Mycobacterium leprae TN, complete genome

Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (TN) was passaged through an armadillo in Tamil Nadu, India, and is the only strain of this species that has been successfully produced in quantities large enough for sequencing and biochemical analyses as the nine-banded armadillo was used as a surrogate host. Causative agent of human leprosy.