Pre_GI: SWBIT SVG BLASTN

Query: NC_008369:1702885 Francisella tularensis subsp. holarctica OSU18, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: Isolated from a beaver that died of tularemia in Oklahoma in 1978. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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BLASTN Alignment.txt

Subject: NC_010167:1287000 Brucella suis ATCC 23445 chromosome II, complete sequence

Lineage: Brucella suis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Human infection usually occurs by accidental contact with infected animals or by ingestion of contaminated food. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.