Query: NC_008369:1702885 Francisella tularensis subsp. holarctica OSU18, complete genome Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria General Information: Isolated from a beaver that died of tularemia in Oklahoma in 1978. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Soil bacterium that can cause opportunistic infections. Ochrobactrum anthropi is an opportunistic human pathogen usually causing infection in association with indwelling medical devices, such as catheters and drainage tubes. This organism and related species have also been isolated from soil, activated sludge, and plants. Ochrobactrum anthropi is a Gram-negative, anaerobic, motile bacterium. A common soil bacteria, it was originally considered as an opportunistic pathogen, causing infections in immunocompromised patients, patients with indwelling catheters or peritoneal dialysis but it is now emerging as a more and more important nosocomial pathogen. The first case of human infection was described in 1980. It has been isolated from blood, the urogenital tract, respiratory tract and eyes, and it can be part of the normal intestinal flora. It is resistant to many antibiotics, especially the beta-lactams.