Query: NC_008369:1702885 Francisella tularensis subsp. holarctica OSU18, complete genome Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria General Information: Isolated from a beaver that died of tularemia in Oklahoma in 1978. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.
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General Information: This strain was collected from the Sargasso Sea at a depth of 10 meters. Phototrophic bacterium. Organisms in this aerobic phototrophic genus are found in marine environments. Members of this group produce bacteriochlorophyll a, which is normally found in anaerobic organisms. One theory to explain this is that the anoxygenic photosynthetic gene cluster was acquired by these organisms via lateral gene transfer. Although they require an organic carbon substrate for growth, they are able to supplement a significant fraction of their metabolic requirements with photosynthetically derviced energy. This species was isolated from a marine cyanobacterial mat. Although they require an organic carbon substrate for growth, they are able to supplement a significant fraction of their metabolic requirements with photosynthetically derviced energy. The presence of the carotenoids bacteriorubixanthinal and erythroxanthin sulfate give this organism a reddish color.