Pre_GI: SWBIT SVG BLASTN

Query: NC_008343:88184 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.

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BLASTN Alignment.txt

Subject: NC_013205:289291 Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446,

Lineage: Alicyclobacillus acidocaldarius; Alicyclobacillus; Alicyclobacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Isolation: Yellowstone National Park, acid hot; Country: USA; Temp: Thermophile; Temp: 60C. Alicyclobacillus acidocaldarius, formerly Bacillus acidocaldarius was first isolated from an acidic creek in Yellowston National Park and grows at a pH of 3.6. This organism is both thermophilic and acidophilic and produces heat and acid stable enzymes, such as amylase and esterase, which may be important in industry.