Query: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Rhodospirillum centenum, also called Rhodocista centenaria, is a nitrogen-fixing photoheterotroph with a complex life cycle. R. centenum is one of the few known thermotolerant purple bacteria species with optimal growth temperature of 44 dgrees C and a maximal growth temperature of 48 degrees C. In liquid media this organism is motile by a single polar flagellum. R. centenum produces lateral flagella to become a swarming cell. Under low nutrient conditions R. centenum forms a desiccation- and UV-resistant cyst. R. centenum can often be cultivated from hot springs such as those found at Yellowstone National Park. R. centenum is emerging as a model organism for genetic and molecular genetic analysis of cyst formation.