Pre_GI: SWBIT SVG BLASTN

Query: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.

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BLASTN Alignment.txt

Subject: NC_010531:428000 Polynucleobacter necessarius STIR1, complete genome

Lineage: Polynucleobacter necessarius; Polynucleobacter; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This strain is an obligate intracellular endosymbiont of the cilliate Euplotes aediculatus. This group of organisms is common in freshwater, comprising up to 60% of the bacteria in freshwater habitats. Polynucleobacter species are also known to be endosymbionts of ciliates. These strains live within the cytoplasm and are essential for their host organisms.