Pre_GI: SWBIT SVG BLASTN

Query: NC_008309:1851189 Haemophilus somnus 129PT, complete genome

Lineage: Histophilus somni; Histophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This strain is an asymptomatic carrier strain that was serum-resistant. Causes disease in cattle. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism is a major cause of disease in feedlot cattle. It causes constriction of blood vessels supplying major organs, restricting blood supply which leads to reduced oxygen delivery, and leads to tissue damage and death. The diseases that result are pneumonia, arthritis, myocarditis (inflammation of heart muscle), and reproductive problems resulting in the loss of millions of dollars in animals each year.

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BLASTN Alignment.txt

Subject: NC_012846:1467446 Bartonella grahamii as4aup, complete genome

Lineage: Bartonella grahamii; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella grahamii (strain as4aup) is Gram-negative bacterium isolated from a wood mouse (Apodemus sylvaticus) in central Sweden. Bartonella are human and animal pathogens which infect erythrocytes and can cause angiogenic lesions. These organisms cause diseases in humans such as Oroya fever, Trench fever, endocarditis, and Cat Scratch disease. Transmission of this organism is via the bite of a blood-sucking arthropod. Bartonella grahamii can be isolated from the blood of rodents and is found world wide. Fleas may be the transmission vector for Bartonella grahamii to other rodents. Human disease appears to be rare and associated with an immunocompromised state.