Query: NC_008011:663958 Lawsonia intracellularis PHE/MN1-00, complete genome Lineage: Lawsonia intracellularis; Lawsonia; Desulfovibrionaceae; Desulfovibrionales; Proteobacteria; Bacteria General Information: Lawsonia intracellularis PHE/MN1-00 was isolated from intestinal mucosal lesions in pigs that had proliferative enteropathy (PE). When introduced into health pigs, this organism produced the clinical and histological signs of PE. Causative agent for proliferative enteropathy in swine. This organism causes proliferative enteropathy (ileitis) in swine and other domesticated animals resulting in severe losses each year. This obligate intracellular pathogen infects the mucosa of the lower intestinal tract by initially infecting crypt cells, which are precursors that normally grow and divide in order to replace the epithelial cells. Once infection occurs, the crypt cells are stimulated to grow and divide abnormally, resulting in the proliferative phenotype. In severe cases of the disease the entire bowel can become affected and persist for up to 40 days, greatly affecting the host animal.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: While pathogenic on Arabidopsis thaliana, it is mainly characterized as causing bacterial speck disease on tomato plants, which has a large economic impact. This organism is mainly endophytic and is a poor colonizes of plant surfaces but can multiply within the host. Bacteria belonging to the Pseudomonas group are common inhabitants of soil and water and can also be found on the surfaces of plants and animals. Pseudomonas bacteria are found in nature in a biofilm or in planktonic form. Pseudomonas bacteria are renowned for their metabolic versatility as they can grow under a variety of growth conditions and do not need any organic growth factors. This species includes many plant pathogens of important crops, which makes it a model organism in plant pathology. Its natural environment is on the surface of plant leaves and it can withstand various stressful conditions, like rain, wind, UV radiation and drought. It can colonize plants in a non-pathogenic state and can rapidly take advantage of changing environmental conditions to induce disease in susceptible plants by shifting gene expression patterns.