Query: NC_007984:221030 Baumannia cicadellinicola str. Hc (Homalodisca coagulata), complete Lineage: Baumannia cicadellinicola; Baumannia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: This newly discovered organism is an obligate endosymbiont of the leafhopper insect Homalodisca coagulata (Say), also known as the Glassy-Winged Sharpshooter, which feeds on the xylem of plants. The insect causes devastation to grape crops and may affect other grasses as it is a vector for the bacterial pathogen, Xylella fastidiosa, which can cause disease in grapevines. Leafhopper insect endosymbiont. Baumannia cicadellinicola is found within bacteriomes, specialized organs in sharpshooter leafhoppers (Cicadellinae), and is transmitted vertically from female to offspring. This bacterium is found within a red-pigmented bacteriome within the host. The bacteria-insect relationship is one of nutritional co-dependence: the bacteria provide important metabolites for the insect's nutritional requirements, and in turn receive a safe environment and metabolites from the insect.
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General Information: This strain (live vaccine strain) was created in the 1960's in the USA and provides protection against tularemia in animal models as well as in humans. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.