Query: NC_007964:717590 Nitrobacter hamburgensis X14, complete genome Lineage: Nitrobacter hamburgensis; Nitrobacter; Bradyrhizobiaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Nitrobacter hamburgensis X14 was isolated from soil. Nitrite-oxidizing soil bacterium. Members of this genus are found in marine, freshwater, and terrestrial habitats, often in association with ammonia-oxidizing bacteria. These organisms oxidize nitrite, generated by the oxidation of ammonia, to nitrate and play an important role in the global nitrogen cycle. The enzyme involved in nitrite oxidation, nitrite oxidoreductase, can also reduce nitrate to nitrite in the absence of oxygen, allowing Nitrobacter sp. to grow anaerobically. Nitrobacter hamburgensis is commonly isolated from freshwater, soil, and sewage sludge. This organism has been used in biofilms to remove nitrogen from wastewater.
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General Information: This serovar has a narrow host range and causes a typhoid-like (paratyphoid fever) illness in humans. It is especially prevalent in southern and eastern Asia, and has been associated with some particularly virulent outbreaks. A number of isolates are increasingly antibiotic resistant. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.