Pre_GI: SWBIT SVG BLASTN

Query: NC_007940:97949 Rickettsia bellii RML369-C, complete genome

Lineage: Rickettsia bellii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain (RML 369-C) was isolated in embryonated chicken eggs from a triturated (powdered) pool of unfed adult Dermacentor variabilis ticks collected from vegetation near Fayetteville, Arkansas, USA, in 1966. Transmitted via American ticks. This organism represents the third group of Rickettsial species and is separate from the spotted fever group and the typhus group. This organism is transovarially transmitted in American ticks and shows the largest range of host organisms including Dermacentor and Amblyomma.

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Subject: NC_008599:1489868 Campylobacter fetus subsp. fetus 82-40, complete genome

Lineage: Campylobacter fetus; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This strain (82-40) was isolated from the blood of a human patient who was having a renal transplant and is the best characterized isolate of this species.. The ratio of bloodstream infection to diarrheal illnesses for C. fetus is nearly 400-fold higher than for C. jejuni, indicating its marked propensity for invasive disease compared to C. jejuni. Causes infertility, infectious abortions in cattle, opportunistic human pathogen. This organism causes infertlity and infectious abortions in domesticated sheep, goats and cattle. It is an opportunistic pathogen in humans which can severely affect immunocompromised patients. Initially the bacterium can cause gastroenteritis, and then spread systemically throughout the blood (bacteremia) and cause septicemia, meningitis, and other systemic infections. This layer is essential for host colonization, and prevents complemented-mediated immune responses by inhibiting complement C3b binding.