Query: NC_007907:2306561 Desulfitobacterium hafniense Y51, complete genome Lineage: Desulfitobacterium hafniense; Desulfitobacterium; Peptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: This strain was isolated from soil contaminated with tetrachloroethene (PCE) in Japan. It can efficiently dehalogenate PCEs via trichloroethene (TCE) to cis-1,2-dichloroethene (cis-1,2-DCE). It can also dehalogenase tetra-, penta-, and hexachloroethanes. Hydrocarbon dehalogenator. This organism can dehalogenate a variety of hydrocarbons and can utilize fumarate, sulfite, and thiosulfate (but not thiousulfate) as terminal electron acceptors. Some important pollutants such as polychlorinated biphenyls (PCBs) may be degraded by this organism.
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General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta by Dr. David Bruce during an epidemic among British soldiers. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.