Pre_GI: SWBIT SVG BLASTN

Query: NC_007880:1667922 Francisella tularensis subsp. holarctica, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This strain (live vaccine strain) was created in the 1960's in the USA and provides protection against tularemia in animal models as well as in humans. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

Subject: NC_011059:2233993 Prosthecochloris aestuarii DSM 271, complete genome

Lineage: Prosthecochloris aestuarii; Prosthecochloris; Chlorobiaceae; Chlorobiales; Chlorobi; Bacteria

General Information: This species is a green sulfur bacterium which forms sedimentary biofilm layers. It has been shown to be associated with coral killed by Black-Band Disease (BBD) a microbial infection of larger coral species. This is a concern for reef conservationists as the larger species are responsible for coral scaffolds, and their reduction by disease would have considerable impact on the reef structure. While there is currently no cause-and-effect link between Prosthecochloris aestuarii and BBD, the species was found on coral which was killed by the disease and was not found on healthy coral or in the surrounding seawater.