Pre_GI: SWBIT SVG BLASTN

Query: NC_007797:914500 Anaplasma phagocytophilum HZ, complete genome

Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

Subject: NC_007760:4055860 Anaeromyxobacter dehalogenans 2CP-C, complete genome

Lineage: Anaeromyxobacter dehalogenans; Anaeromyxobacter; Myxococcaceae; Myxococcales; Proteobacteria; Bacteria

General Information: This strain differs from other isolates based on the combination of its ability to use 2,5-dichlorophenol and its inability to use nitrate as a strong electron acceptor. It can also dechlorinate 2,4-dichlorophenol and 2,4,6-trichlorophenol much faster than other isolates. Can dehalogenate chlorinated phenols. This anaerobic species was originally isolated by enrichment and isolation of single plate-grown colonies, and was the first pure culture of myxobacteria able to grow anaerobically.