Query: NC_007759:723675 Syntrophus aciditrophicus SB, complete genome Lineage: Syntrophus aciditrophicus; Syntrophus; Syntrophaceae; Syntrophobacterales; Proteobacteria; Bacteria General Information: Syntrophus aciditrophicus SB was isolated from sludge from a sewage treatment plant in Norman, Oklahoma, USA. Syntrophic benzoate-oxidizing bacterium. Syntrophus aciditrophicus is able to ferment benzoate when grown in co-culture with hydrogen-consuming methanogens (syntrophic metabolism).
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General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.