Query: NC_007716:467235 Aster yellows witches'-broom phytoplasma AYWB, complete genome Lineage: Aster yellows witches'-broom phytoplasma; Phytoplasma; Acholeplasmataceae; Acholeplasmatales; Tenericutes; Bacteria General Information: Mycoplasma-like plant pathogen. Aster yellows witches'-broom phytoplasma belongs to a group of mycoplasma-like organisms that infect plants and insects. Phytoplasmas are insect-transmitted plant pathogens that cause economically important diseases in many plant species, including vegetables, ornamentals, and fruit crops. Aster yellows is a sporadic disease of vegetable crops and is transmitted by the aster leafhopper.
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General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.