Query: NC_007514:904565 Chlorobium chlorochromatii CaD3, complete genome Lineage: Chlorobium chlorochromatii; Chlorobium; Chlorobiaceae; Chlorobiales; Chlorobi; Bacteria General Information: Chlorobium chlorochromatii CaD3 was isolated from a phototrophic consortia obtained from a freshwater lake in Germany. Chlorobium chlorochromatii is an green sulfur bacterium isolated from low temperature anaerobic fresh water habitats. This organism grows as part of a phototrophic consortium which consists of a colorless central bacterium surrounded by chlorosome-containing green sulfur epibionts. This organism is able to be grown in pure culture therefore is not an obligate symbiont. This organism is an obligate anaerobic phototroph able to fix nitrogen.
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General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta by Dr. David Bruce during an epidemic among British soldiers. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.