Query: NC_007354:534865 Ehrlichia canis str. Jake, complete genome
Lineage: Ehrlichia canis; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.
Subject: NC_010376:606000 Finegoldia magna ATCC 29328, complete genome
Lineage: Finegoldia magna; Finegoldia; Clostridiales Family XI; Clostridiales; Firmicutes; Bacteria
General Information: It is isolated most frequently from various infection sites, including soft tissue, bone and joint, and diabetic foot infections. This species, formerly Peptostreptococcus magnus, is a commensal bacterium colonizing human skin and mucous membranes. It has been shown to cause valve endocarditic in humans. Gram-positive anaerobic cocci (GPAC) are a major part of the normal human flora colonizing skin and mucous membranes of the mouth and gastrointestinal tracts. In GPAC, Finegoldia magna (formerly Peptostreptococcus magnus) has the highest pathogenicity and is isolated most frequently from various infection sites, including soft tissue, bone and joint, and diabetic foot infections.