Query: NC_006832:978837 Ehrlichia ruminantium str. Welgevonden, complete genome Lineage: Ehrlichia ruminantium; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria General Information: This strain was obtained from an infected tick and maintained by serial infection in mice. Obligate intracellular bacterium and causative agent of heartwater. This organism causes heartwater, a disease with a high mortality rate that affects both wild and domesticated ruminants in sub-Saharan Africa and parts of the Caribbean. The name heartwater refers to the hydropericardium (excessive fluid in the sac surrounding the heart) commonly found associated with infection. This organism is found in membrane-bound vacuoles in endothelial cells and neutrophils and is an obligate intracellular parasite.
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General Information: This strain (RML 369-C) was isolated in embryonated chicken eggs from a triturated (powdered) pool of unfed adult Dermacentor variabilis ticks collected from vegetation near Fayetteville, Arkansas, USA, in 1966. Transmitted via American ticks. This organism represents the third group of Rickettsial species and is separate from the spotted fever group and the typhus group. This organism is transovarially transmitted in American ticks and shows the largest range of host organisms including Dermacentor and Amblyomma.