Pre_GI: SWBIT SVG BLASTN

Query: NC_006814:1618588 Lactobacillus acidophilus NCFM, complete genome

Lineage: Lactobacillus acidophilus; Lactobacillus; Lactobacillaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This organism is a normal inhabitant of the human intestinal tract. This strain was isolated from a human in 1970. Normal gastrointestinal bacterium. They are commonly found in the oral, vaginal, and intestinal regions of many animals. They are important industrial microbes that contribute to the production of cheese, yogurt, and other products such as fermented milks, all stemming from the production of lactic acid, which inhibits the growth of other organisms as well as lowering the pH of the food product. Industrial production requires the use of starter cultures, which are carefully cultivated, created, and maintained, which produce specific end products during fermentation that impart flavor to the final product, as well as contributing important metabolic reactions, such as the breakdown of milk proteins during cheese production. The end product of fermentation, lactic acid, is also being used as a starter molecule for complex organic molecule syntheses. This organism has been studied for its ability to help the human gut maintain its natural microbial community. Strains of this organism are also used in the production of yogurt, cheese and other fermented foods.

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BLASTN Alignment.txt

Subject: NC_008309:1827809 Haemophilus somnus 129PT, complete genome

Lineage: Histophilus somni; Histophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This strain is an asymptomatic carrier strain that was serum-resistant. Causes disease in cattle. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism is a major cause of disease in feedlot cattle. It causes constriction of blood vessels supplying major organs, restricting blood supply which leads to reduced oxygen delivery, and leads to tissue damage and death. The diseases that result are pneumonia, arthritis, myocarditis (inflammation of heart muscle), and reproductive problems resulting in the loss of millions of dollars in animals each year.