Query: NC_006569:69939 Silicibacter pomeroyi DSS-3 megaplasmid, complete sequence Lineage: Ruegeria pomeroyi; Ruegeria; Rhodobacteraceae; Rhodobacterales; Proteobacteria; Bacteria General Information: Formerly Silicibacter pomeroyi, his marine bacterium is a member of the Roseobacter clade and was isolated off of the coast of Georgia in 1998. Dimethylsulfoniopropionate-degrading bacterium. Ruegeria pomeroyi is capable of degrading the organic sulfur compound DMSP (dimethylsulfoniopropionate) and can metabolize a number of sulfur compounds. DMSP is synthesized by marine algae and the degradation product dimethylsulfide contributes to the global sulfur cycle.
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General Information: This strain was originally isolated from a patient with whooping cough and has been studied extensively for over 40 years. Causative agent of whooping cough. This group of organisms is capable of invading the respiratory tract of animals and causing severe diseases. They express a number of virulence factors in order to do this including filamentous hemagglutins for attachment, cytotoxins, and proteins that form a type III secretion system for transport of effector molecules into host cells. This organism, which is unable to persist in the environment, is a strict human pathogen that causes whooping cough. Once a common cause of death in children the development of a vaccine has greatly decreased the number of deaths due to Bordetella pertussis. However, this organism infects and estimated 39 million people and kills hundreds of thousands of people each year.