Pre_GI: SWBIT SVG BLASTN

Query: NC_006513:38818 Azoarcus sp. EbN1, complete genome

Lineage: Aromatoleum aromaticum; Aromatoleum; Rhodocyclaceae; Rhodocyclales; Proteobacteria; Bacteria

General Information: First isolated from sediment contaminated with ethylbenzene, this organism is capable of growing on crude oil, using polar aromatic compounds such as benzoate under both oxic and anoxic conditions. It is currently being evaluated for use in aromatic hydrocarbon bioremediation projects. Aromatic hydrocarbon-degrading bacterium. Capable of metabolizing various aromatic hydrocarbons, including toluene and ethylbenzene and may be of use in bioremediation.

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BLASTN Alignment.txt

Subject: NC_004741:2593012 Shigella flexneri 2a str. 2457T, complete genome

Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a highly virulent strain that has been widely used for genetic and clinical research. Causes enteric disease. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.