Query: NC_006361:4098469 Nocardia farcinica IFM 10152, complete genome Lineage: Nocardia farcinica; Nocardia; Nocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: This type strain was isolated from the bronchus of a male Japanese patient. Opportunistic human pathogen. This genus was originally described from specimens isolated by plating soil suspensions on diagnostic sensitivity test plates augmented with antifungal agents. Organisms in this genus cause opportunistic human pulmonary and systemic nocardiosis. This can complicate existing debilitating conditions such as leukemia, lymphoma, or other neoplasms, or illnesses in patients with compromised immune systems.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.