Pre_GI: SWBIT SVG BLASTN

Query: NC_006274:3697255 Bacillus cereus E33L, complete genome

Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (originally ZK, now E33L; Ethosha National Park, Namibia; isolate number 33; Large colony) was isolated from a swab of a dead zebra carcass in April, 1996. Soil microorganism that can cause food poisoning. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

Subject: NC_008023:1398085 Streptococcus pyogenes MGAS2096, complete genome

Lineage: Streptococcus pyogenes; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: Isolated from a patient with acute poststreptococcal glomerulonephritis in 1993. Causes tonsilitis. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is a member of the normal human nasopharyngeal flora. S. pyogenes is a group A streptococcus and is the leading cause of uncomplicated bacterial pharyngitis and tonsillitis. This organism is commonly referred to by the lay press as "flesh eating bacteria".