Pre_GI: SWBIT SVG BLASTN

Query: NC_006155:456000 Yersinia pseudotuberculosis IP 32953, complete genome

Lineage: Yersinia pseudotuberculosis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a fully virulent serotype I strain isolated from a human patient. Environmental bacterium that causes gastrointestinal disease. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. This organism was first isolated in 1883 by Malassez and Vignal and is termed pseudotuberculosis since it causes lesions in the lung that are similar to those observed during tuberculosis infection. It is ubiquitous in the environment and is a food and waterborne pathogen that affects animals as well as humans by causing gastroenteritis like Yersinia enterocolitica.

Subject: NC_002927:383760 Bordetella bronchiseptica RB50, complete genome

Lineage: Bordetella bronchiseptica; Bordetella; Alcaligenaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This strain was isolated from a rabbit. Causes a respiratory illness in animals. This group of organisms is capable of invading the respiratory tract of animals and causing severe diseases. They express a number of virulence factors in order to do this including filamentous hemagglutinins for attachment, cytotoxins, and proteins that form a type III secretion system for transport of effector molecules into host cells. Bordetella bronchiseptica, which is one of the few Bordetella that is capable of persisting in the environment, is rarely found in humans and is often associated with animals. This organism cause respiratory disease most commonly in pigs, rabbits and dogs.