Pre_GI: SWBIT SVG BLASTN

Query: NC_006142:33268 Rickettsia typhi str. Wilmington, complete genome

Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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BLASTN Alignment.txt

Subject: NC_014935:1047411 Nitratifractor saLSUginis DSM 16511 chromosome, complete genome

Lineage: Nitratifractor salsuginis; Nitratifractor; ; Campylobacterales; Proteobacteria; Bacteria

General Information: Country: Japan; Isolation: Deep-sea hydrothermal vent chimney; Temp: Mesophile; Temp: 37C. This organism was isolated from the Iheya North hydrothermal field inthe Mid-Okinawa Trough, Japan. It is a strict chemolithoautotroph, growing byrespiratory nitrate reduction with H2, forming N2 as a metabolic product.