Pre_GI: SWBIT SVG BLASTN

Query: NC_006142:33268 Rickettsia typhi str. Wilmington, complete genome

Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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BLASTN Alignment.txt

Subject: NC_014363:480049 Olsenella uli DSM 7084 chromosome, complete genome

Lineage: Olsenella uli; Olsenella; Coriobacteriaceae; Coriobacteriales; Actinobacteria; Bacteria

General Information: Isolation: Human gingival crevice; Temp: Mesophile; Temp: 37C. The bacteria are nonmotile, Gram-positive rods that occur singly, in pairs, and in short chains; the central part of the cell may swell particularly when grown on solid medium. This strain is microaerotolerant to anaerobic and grows optimally at 37 degrees Celsius. Olsenella uli (formerly Lactobacillus uli) has been isolated from human gingival crevices and periodontal pockets.