Pre_GI: SWBIT SVG BLASTN

Query: NC_005956:699206 Bartonella henselae str. Houston-1, complete genome

Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.

- Sequence; - BLASTN hit (Low score = Light, High score = Dark)
- hypothetical protein; - cds: hover for description

BLASTN Alignment.txt

Subject: NC_007912:1173752 Saccharophagus degradans 2-40, complete genome

Lineage: Saccharophagus degradans; Saccharophagus; Alteromonadaceae; Alteromonadales; Proteobacteria; Bacteria

General Information: This strain is a marine gamma-proteobacterium that was isolated from decaying Spartina alterniflora, a salt marsh cord grass, in the Chesapeake Bay, USA. Saccharophagus degradans 2-40 has been used to produce ethanol from plant material and may be useful for the production bioethanol. Bacterium able to degrade complex carbohydrates. Saccharophagus degradans is capable of degrading insoluble complex carbohydrates through the collective action of enzyme complexes found on its cell surfaces, utilizing the degradation products as a carbon source. This organism may be useful in bioremediation. The degradative enzymes this organism produces are typically exoenzymes that are collected and organized into large surface complexes termed cellulosomes.