Pre_GI: SWBIT SVG BLASTN

Query: NC_005085:4499500 Chromobacterium violaceum ATCC 12472, complete genome

Lineage: Chromobacterium violaceum; Chromobacterium; Chromobacteriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Chromobacterium violaceum ATCC 12472 was isolated from freshwater in Malaya. Common tropical soil bacterium. This facultative organism is an abundant environmental bacterium that lives in tropical and subtropical regions in the soil and water. It has exploitable properties including the ability to produce a bactericidal purple pigment, violacein, as well as the ability to produce a bioplastic and to biologically solubilize gold from the environment. It is occasionally pathogenic in immunocompromised individuals or children where it may cause diarrhea, but sometimes causes septicemia and is at times fatal.

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BLASTN Alignment.txt

Subject: NC_010263:925500 Rickettsia rickettsii str. Iowa, complete genome

Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.