Query: NC_005085:4499500 Chromobacterium violaceum ATCC 12472, complete genome Lineage: Chromobacterium violaceum; Chromobacterium; Chromobacteriaceae; Neisseriales; Proteobacteria; Bacteria General Information: Chromobacterium violaceum ATCC 12472 was isolated from freshwater in Malaya. Common tropical soil bacterium. This facultative organism is an abundant environmental bacterium that lives in tropical and subtropical regions in the soil and water. It has exploitable properties including the ability to produce a bactericidal purple pigment, violacein, as well as the ability to produce a bioplastic and to biologically solubilize gold from the environment. It is occasionally pathogenic in immunocompromised individuals or children where it may cause diarrhea, but sometimes causes septicemia and is at times fatal.
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General Information: This strain was isolated from a human in South Africa. Causative agent for Rocky Mountain spotted fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes Rocky Mountain spotted fever which can cause severe damage to the endothelial layer of major organs, including the lungs, heart, kidneys, and skeletal muscle which can result in death.