Query: NC_004606:623853 Streptococcus pyogenes SSI-1, complete genome Lineage: Streptococcus pyogenes; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: This strain is a serotype M3 strain that was isolated from a toxic-shock patient in Japan and often associated with severe invasive infections, necrotizing fasciitis, and death. Causes tonsilitis. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is a member of the normal human nasopharyngeal flora. Group A streptococcus and is the leading cause of uncomplicated bacterial pharyngitis and tonsillitis. This organism is commonly referred to by the lay press as "flesh eating bacteria".
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General Information: Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Causes meningitis and sepsis in newborns. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is the leading cause of meningitis and sepsis in newborns. Additionally this organism is the cause of serious infections in immunocompromised adults. S. agalactiae is able to asymptomatically colonize human skin and mucous membranes. This organism is also implicated in cases of mastitis in cows.