Pre_GI: SWBIT SVG BLASTN

Query: NC_004603:3080614 Vibrio parahaemolyticus RIMD 2210633 chromosome I, complete

Lineage: Vibrio parahaemolyticus; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: This is a clinical strain isolated in 1996 in Osaka, Japan. It contains a type III secretion system which may enable colonization and penetration of the host intestinal epithelial layer, and possibly lead to septicemia. The genome contains multipe chromosomal rearrangements as compared to Vibrio cholerae. The organism also produces a hemolysin (thermostable direct hemolysin - TDH) that is particular to Vibrio parahaemolyticus. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. This species causes food poisoning (gastroenteritis) in countries that have elevated levels of seafood consumption such as Japan.

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BLASTN Alignment.txt

Subject: NC_002952:582365 Staphylococcus aureus subsp. aureus MRSA252, complete genome

Lineage: Staphylococcus aureus; Staphylococcus; Staphylococcaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain is a hospital-acquired strain isolated in the United Kingdom, representative of the methicillin-resistant (MRSA) strains. It is one of the two major MRSA strains found in British hospitals in the late 1990's. Causes skin infections. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. Continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.