Pre_GI: SWBIT SVG BLASTN

Query: NC_004603:1115134 Vibrio parahaemolyticus RIMD 2210633 chromosome I, complete

Lineage: Vibrio parahaemolyticus; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: This is a clinical strain isolated in 1996 in Osaka, Japan. It contains a type III secretion system which may enable colonization and penetration of the host intestinal epithelial layer, and possibly lead to septicemia. The genome contains multipe chromosomal rearrangements as compared to Vibrio cholerae. The organism also produces a hemolysin (thermostable direct hemolysin - TDH) that is particular to Vibrio parahaemolyticus. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. This species causes food poisoning (gastroenteritis) in countries that have elevated levels of seafood consumption such as Japan.

Subject: NC_013416:1429881 Aggregatibacter actinomycetemcomitans D11S-1, complete genome

Lineage: Aggregatibacter actinomycetemcomitans; Aggregatibacter; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: Aggregatibacter actinomycetemcomitans D11S-1 was recovered from a subject with aggressive periodontitis. Aggregatibacter actinomycetemcomitans, previously Actinobacillus actinomycetemcomitans typically resides in the oral cavity of humans and animals and can cause a number of diseases. The bacterium, along with 3 other organisms, is the main culprit in periodontis, which results in devastation to the bone supporting the teeth. Adherence to oral surfaces is controlled through the tad (tight adherence) locus, which may express proteins that are involved in type IV secretion.