Pre_GI: SWBIT SVG BLASTN

Query: NC_004459:767127 Vibrio vulnificus CMCP6 chromosome I, complete sequence

Lineage: Vibrio vulnificus; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Pathogen in immunocompromised patients. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Organisms of this species are opportunistic pathogens that can attack immunocompromised patients and causes gastroenteritis (inflammation of mucous membranes of stomach and intestine), wound infections, and primary septicemia (spread of the organism through the blood). This organism is the major cause of death from eating raw oysters, especially in people with liver damage. It only affects humans and other primates.

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BLASTN Alignment.txt

Subject: NC_011083:2200613 Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,

Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a multidrug resistant strain. Salmonella enterica subsp. enterica serovar Heidelberg is one of the more common serovars causing disease in the USA. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.