Query: NC_004368:726385 Streptococcus agalactiae NEM316, complete genome Lineage: Streptococcus agalactiae; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: This strain is a serotype III strain isolated from a case of fatal septicemia. Type III is responsible for 80% of neonatal GBS (group B streptococcal) meningitis. Causes meningitis and sepsis in newborns.Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is the leading cause of meningitis and sepsis in newborns. Additionally this organism is the cause of serious infections in immunocompromised adults. Able to asymptomatically colonize human skin and mucous membranes. This organism is also implicated in cases of mastitis in cows.
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General Information: This strain is a methicillin-resistant (MRSA) strain with vancomycin resistance (VRSA) isolated in 1997 from the pus of a Japanese male baby with a surgical wound infection that did not respond to vancomycin. Causes skin infections. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. S. aureus continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.