Query: NC_004342:756942 Leptospira interrogans serovar Lai str. 56601 chromosome I,
Lineage: Leptospira interrogans; Leptospira; Leptospiraceae; Spirochaetales; Spirochaetes; Bacteria
General Information: Pathogenic strain. Causative agent of leptospirosis. This organism is the causative agent of leptospirosis, a tropical zoonosis transmitted by direct contact with the urine of infected animals. This motile and obligately aerobic organism grows optimally at 28-30 C. Many serovars are adapted for specific mammalian reservoir hosts, which harbor the organisms in their renal tubules and shed them in their urine. Because of the large spectrum of animal species that serve as reservoirs, leptospirosis is considered to be the world's most widespread zoonotic disease.
Subject: NC_002946:1786000 Neisseria gonorrhoeae FA 1090, complete genome
Lineage: Neisseria gonorrhoeae; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: A serum-resistant streptomycin-resistant proline-requiring strain isolated from a patient with disseminated gonococcal infections. Causes gonorrhea. One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.