Pre_GI: SWBIT SVG BLASTN

Query: NC_004311:1096649 Brucella suis 1330 chromosome II, complete sequence

Lineage: Brucella suis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.

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Subject: NC_014448:9419 Mycoplasma hyorhinis HUB-1 chromosome, complete genome

Lineage: Mycoplasma hyorhinis; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria

General Information: Mycoplasma hyorhinis HUB-1 was isolate from the respiratory tract of swine. Mycoplasma hyorhinis, though generally considered being a swine pathogen, is found most commonly infecting laboratory cell lines including human cells. Recently, an increasing body of work suggests that chronic infections of M. hyorhinis may cause oncogenic transformation. Infection with mycoplasma is a common problem in cell cultures, with Mycoplasma hyorhinis being the predominant species.