Query: NC_003911:3453764 Silicibacter pomeroyi DSS-3, complete genome Lineage: Ruegeria pomeroyi; Ruegeria; Rhodobacteraceae; Rhodobacterales; Proteobacteria; Bacteria General Information: Formerly Silicibacter pomeroyi, his marine bacterium is a member of the Roseobacter clade and was isolated off of the coast of Georgia in 1998. Dimethylsulfoniopropionate-degrading bacterium. Capable of degrading the organic sulfur compound DMSP (dimethylsulfoniopropionate) and can metabolize a number of sulfur compounds. DMSP is synthesized by marine algae and the degradation product dimethylsulfide contributes to the global sulfur cycle.
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General Information: This strain was isolated from an infected goat and is pathogenic in humans. Causes brucellosis and undulant fever. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a facultative intracellular bacteria that causes abortion in wild and domestic animals, usually goats or sheep, and undulant fever in humans. Brucellosis is a major health problem in the Mediterranean region and parts of Asia, Africa, and Latin America, where it causes severe economic losses. The disease is transmitted to humans by nonpasteurized milk and milk products or by direct contact with infected animals or carcasses.