Query: NC_003869:2143892 Thermoanaerobacter tengcongensis MB4, complete genome Lineage: Caldanaerobacter subterraneus; Caldanaerobacter; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria General Information: This organism was originally isolated from a hot spring in Tengcong, China, and is the type strain for the species. Genomic analysis indicates it is similar to Bacillus halodurans and that it has one of the most biased leading strand distribution of genes. Although the organism has not been observed to be motile or to sporulate, it does contain genes for both functions. The bacterium produces acetate and ethanol from glucose and cannot degrade xylan and cellulose.
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General Information: This strain was obtained from an infected tick and maintained by serial infection in mice. Obligate intracellular bacterium and causative agent of heartwater. This organism causes heartwater, a disease with a high mortality rate that affects both wild and domesticated ruminants in sub-Saharan Africa and parts of the Caribbean. The name heartwater refers to the hydropericardium (excessive fluid in the sac surrounding the heart) commonly found associated with infection. This organism is found in membrane-bound vacuoles in endothelial cells and neutrophils and is an obligate intracellular parasite.