Query: NC_003454:249304 Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete Lineage: Fusobacterium nucleatum; Fusobacterium; Fusobacteriaceae; Fusobacteriales; Fusobacteria; Bacteria General Information: Normal oral and gastrointestinal bacterium. This genus contains mostly obligately anaerobic bacilli. Many of the isolates are spindle-shaped, or fusiform. This organism belongs to the normal microflora of the human oral and gastrointestinal tracts. It is a very long and slender spindle-shaped bacillus with sharply pointed ends that is characterized by the ability to invade soft tissues. It acts as a bridge between early and late colonizers of the tooth surface, and exerts synergism with other bacteria in mixed infections. It is most frequently associated with periodontal diseases, as well as with some invasive human infections of the head and neck, chest, lung, liver and abdomen, and some anginas. One of the major amino acid and sugar fermentation pathways in Fusobacterium nucleatum produces butyric and acetic acids.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This organism was discovered in 1819 by Bizio who named the organism after the Italian physicist Serrati. It was considered a nonpathogenic organism until late in the 20th century, although pathogenicity was noted as early as 1913. Serratia marcescens is an opportunistic human pathogen that is increasingly associated with life-threatening hospital-acquired infections. It is an environmental organism that has a broad host range, and is capable of infecting vertebrates and invertebrates, as well as plants. In humans, Serratia marcescens can cause meningitis (inflammation of the membrane surrounding the brain and spinal cord), endocarditis (inflammation of heart muscle) and pyelonephritis (inflammation of the kidneys). Many strains are resistant to multiple antibiotics. Environmental isolates are noted by production of the red pigment prodigiosin.